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Elsevier, Psychiatry Research, 2-3(190), p. 367-368

DOI: 10.1016/j.psychres.2011.06.009

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Association study of DRD3 gene in schizophrenia in Mexican sib-pairs

Journal article published in 2011 by Nora Urraca, Beatriz Camarena ORCID, Alejandro Aguilar, Ana Fresán, Rogelio Apiquián ORCID, Lorena Orozco, Alessandra Carnevale, Humberto Nicolini
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Abstract

Schizophrenia is a heritable, complex mental disorder. We analysed the DRD3 gene as a candidate to be related to schizophrenia and clinical features in affected sib-pairs. A positive association with the -250A/Ser9 haplotype and a trend toward an association with formal thought disorder were observed. A synergic effect of DRD3 polymorphisms on schizophrenia susceptibility is suggested.