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Elsevier, Tetrahedron Letters, 16(49), p. 2642-2645, 2008

DOI: 10.1016/j.tetlet.2008.02.087

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Chemoenzymatic preparation of nucleosides from furanoses

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Chemoenzymatic preparation of ribose, deoxyribose and arabinose 5-phosphates was accomplished. These compounds were tested as starting materials in the enzymatic preparation of natural and modified purine and pyrimidine nucleosides, using an overexpressed Escherichia coli phosphopentomutase.