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Bulletin of Advance Scientific Research 01 [01] (2015) Study of correlation between intraoperative crush smears, frozen section diagnosis and biopsy results of intracranial lesions

Journal article published in 2015 by Tanushri Mukherjee, Parikshit Sanyal, T. J. Rapaii, Atoshi Basu
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Crush cytology and frozen sections of intracranial space occupying lesions (ICSOLs) are an effective and time saving tool for intra operative consultation. In a stereotactic biopsy, it enables the pathologist to rightly comment whether (a) brain tissue is there or not in the biopsy, (b) possible nature of the lesion. In a resection for an ICSOL, the techniques help the surgeon with an intra operative working diagnosis. The present study attempts to validate the diagnostic accuracy of the two methods with histopathological diagnosis as the Gold standard. Similar studies have been carried out in India recently, notably from a group in Jammu who attained a crush smear diagnostic accuracy of 95.36% in a series of 151 cases[1]. In another series of 114 cases, diagnostic accuracy of crush crush smear was found to be 88.5% (85/96) and the accuracy on FS diagnosis was 90.6% (87/96), with 84.9% in the group of glial tumors[2]. A similar diagnostic accuracy was achieved in a series of 183 tumors, where crush smears yielded the right diagnosis in 89.7% (140/156). The accuracy of FS diagnosis was 90.4%[3].