This paper presents the results of an ongoing research on key properties of self-consolidating lightweight concrete (SCLC) containing high-volume pumice powder. The use of lightweight aggregates in the production of SCC combines the favorable properties of LWC and SCC in self-consolidating lightweight concrete. The purpose of this study is to investigate key properties of low-cost and environmental friendly SCLC using pumice powder as replacement of cement in different contents. In this study, self-consolidating lightweight concrete containing five different contents of pumice powder as replacement of cement (0, 15, 30, 40 and 50 by weight of total cementitious material) are examined. The fresh properties of SCLCs were observed through slump flow time and diameter, V-funnel flow time and J-ring tests. The compressive strength and splitting tensile strength were measured at 7, 28, 56 and 91 days as strength properties. Permeability (water penetration depth), water absorption, sorptivity (rate of water absorption) and pulse velocity tests were investigated for various SCLC mixtures at 91 days as transport properties and durability indexes. Moreover, drying shrinkage was measured in SCLCs containing different contents of pumice powder and compared with that of the control mixture. It has been found that it is possible to achieve a low-cost and environmental friendly SCLC using high volume of pumice powder in the mixture. Despite a decrease in strength properties by increasing the pumice powder content, SCLCs had still structural strength and acceptable durability.