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Revista da Associação Médica Brasileira (English Edition), 3(58), p. 376-382

DOI: 10.1016/s2255-4823(12)70210-2

Elsevier, Revista da Associação Médica Brasileira, 3(58), p. 376-382, 2012

DOI: 10.1590/s0104-42302012000300020

Elsevier, Revista da Associação Médica Brasileira, 3(58), p. 376-382, 2012

DOI: 10.1016/s0104-4230(12)70210-5

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Atualidades proteômicas na sepse

Journal article published in 2012 by Rodrigo Siqueira-Batista, Eduardo Gomes de Mendonça, Eduardo Gomes de Mendonça ORCID, Maria Goreti de Almeida Oliveira, Andréia Patrícia Gomes, Andréia Patrícia Gomes, Rodrigo Roger Vitorino, Rodrigo Roger Vitorino, Renato Miyadahira, Mario Castro Alvarez-Perez, Maria Goreti de Almeida Oliveira
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The increased knowledge regarding proteomic analysis techniques has allowed for better understanding of the molecular bases related to the identification of cell signaling, modifying protein, and post-translational modification pathways, in addition to the characterization of specific biological markers. Thus, documenting certain proteins expressed in sepsis is a promising approach to elucidate pathophysiological, diagnostic, therapeutic, and prognostic aspects in this condition with a purpose of applying them to clinical practice. Although the studies are still preliminary, proteomics may offer good benefits for the better management of septic patients. Thus, this article aims to introduce a short review of the applications of proteomic studies to sepsis.