Oxazoline cuprate addition to nitroalkenes: a new route approaching γ-amino acids

Simonelli, Fabio; dos Santos, Alcindo A.; de Oliveira, Alfredo R. M.; de A. Marques, Francisco; Clososki, Giuliano C.; Dos Santos, A. A.; Oliveira, Alfredo R. M. de; Marques, Francisco de A.; Zarbin, Paulo H. G.

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Elsevier, Tetrahedron Letters, 42(42), p. 7375-7378

DOI: 10.1016/s0040-4039(01)01576-3

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Oxazoline cuprate addition to nitroalkenes: a new route approaching γ-amino acids

Journal article published in 2001 by Fabio Simonelli, Alcindo A. dos Santos, Alfredo R. M. de Oliveira, Francisco de A. Marques, Giuliano C. Clososki

, A. A. Dos Santos, Alfredo R. M. de Oliveira

, Francisco de A. Marques, Paulo H. G. Zarbin

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Abstract

Current studies of oxazoline cyanocuprates addition to conjugated nitroalkenes, and their improved reactivity when compared to lithium oxazoline anions, has shown to be an efficient method for the synthesis of a variety of γ-nitrooxazolines, an interesting intermediate of γ-amino acids.

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Oxazoline cuprate addition to nitroalkenes: a new route approaching γ-amino acids

Abstract