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American Chemical Society, Organic Letters, 12(3), p. 1905-1908, 2001

DOI: 10.1021/ol015951b

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Alkynoates as a Source of Reactive Alkylinides for Aldehyde Addition Reactions

This paper is available in a repository.
This paper is available in a repository.

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Abstract

[see reaction]. The reaction of activated alkynes with carbonyl compounds in the presence of a catalytic amount of a nucleophile leads to enol-protected functionalized propargyl alcohols and 1,3-dioxolane compounds by way of a mild carbon-carbon bond formation reaction.