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Taylor and Francis Group, JAK-STAT, 2(2), p. e23203

DOI: 10.4161/jkst.23203

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Why should we care about fly tumors?

Journal article published in 2013 by James Castelli-Gair Hombría ORCID, Florenci Serras
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Drosophila is proving to be a valuable model for studying aggressive tumors induced by the combined activation of EGFR and JAK-STAT signaling. Here we summarize some of the most recent data showing that tissue damage and the modulation of common pathway regulators are at the heart tumor progression and metastasis.