Published in
American Association for the Advancement of Science, Science Translational Medicine, 297(7), 2015
DOI: 10.1126/scitranslmed.aab1482
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Inhibition of the alternative complement pathway preserves photoreceptors after retinal injury
Journal article published in 2015 by
J. Harry Sweigard,
J. Harry Sweigard,
Hidetaka Matsumoto,
Kaylee E. Smith,
Leo A. Kim 
,
Eleftherios I. Paschalis,
Yoko Okonuki,
Alexandra Castillejos,
Keiko Kataoka,
Eiichi Hasegawa,
Ryoji Yanai,
Deeba Husain,
John D. Lambris,
Demetrios Vavvas,
Joan W. Miller
and other authors.
,
Eleftherios I. Paschalis,
Yoko Okonuki,
Alexandra Castillejos,
Keiko Kataoka,
Eiichi Hasegawa,
Ryoji Yanai,
Deeba Husain,
John D. Lambris,
Demetrios Vavvas,
Joan W. Miller
and other authors.
This paper is available in a repository.
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Abstract
The alternative complement pathway is activated in response to retinal injury, and inhibiting this pathway prevents complement-mediated photoreceptor cell death.