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Wiley, Hepatology, 5(43), p. 1152-1154, 2006

DOI: 10.1002/hep.21165

Elsevier, Digestive and Liver Disease, (38), p. S34

DOI: 10.1016/s1590-8658(06)80086-1

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A novel multidrug-resistance protein 2 gene mutation identifies a subgroup of patients with primary biliary cirrhosis and pruritus

Journal article published in 2006 by Isabella Carderi, Annarosa Floreani, Angela Variola ORCID, Nora V. Bergasa, Erik Rosa Rizzotto, James Nicol
This paper is available in a repository.
This paper is available in a repository.

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Abstract

A single nucleotide polymorphism characterized by the substitution of valine for glutamate (V1188E) in exon 25 of the multidrug resistance protein 2 gene was found in a group of patients with primary biliary cirrhosis. This heterozygous mutation was significantly associated with the presence of pruritus.