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Oxford University Press, Nucleic Acids Research, Database(36), p. D267-D270, 2007

DOI: 10.1093/nar/gkm852

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OPTIC: orthologous and paralogous transcripts in clades

Journal article published in 2007 by Andreas Heger ORCID, Chris P. Ponting ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The genome sequences of a large number of metazoan species are now known. As multiple closely related genomes are sequenced, comparative studies that previously focussed on only pairs of genomes can now be extended over whole clades. The orthologous and paralogous transcripts in clades (OPTIC) database currently provides sets of gene predictions and orthology assignments for three clades: (i) amniotes, including human, dog, mouse, opossum, platypus and chicken (17 443 orthologous groups); (ii) a Drosophila clade of 12 species (12 889 orthologous groups) and (iii) a nematode clade of four species (13 626 orthologous groups). Gene predictions, multiple alignments and phylogenetic trees are freely available to browse and download from http://genserv.anat.ox.ac.uk/clades. Further genomes and clades will be added in the future.