New Intelligent Transport System (ITS) applications such as the Digital Tachograph (DT) require reliable Global Navigation Satellite System (GNSS) signals to perform their activities. However, communication and navigation signal reception is vulnerable to several forms of interference. Brute-force jamming is a form of intentional interference where powerful signals are broadcast in the frequency bands used by the victim receiver. In this way, the receiver is unable to operate having a cascade effects on ITS. A solution against jamming is the development of pre-correlation techniques which exploit the Interference Cancellation (IC) principle. In this paper, a real-time Software Defined Radio (SDR) platform able to mitigate the impact of jamming is developed. The platform is fully reconfigurable and implements several mitigation techniques such as notch filtering and pulse blanking. The tests performed using a real GNSS jammer show that the platform developed is an effective solution which can be easily applied to the road transportation sector.