People with neck pain as well as people with neck pain plus related headache that lasted at least one month, who received multimodal care that included exercises plus mobilisation [movement imposed onto joints and muscles] or manipulation [adjustments] reported greater pain reduction, improved ability to perform everyday activities and an increase in their perceived effects of treatment than those who received no treatment. This review of 33 trials did not favour manipulation or mobilisation done alone or in combination with various other physical medicine agents. It was unclear if manipulation and mobilisation performed in combination were beneficial, but when compared to one another, neither was superior.