Gold-198 (β max= 0.96 MeV (98.6%), γ max = 0.412 MeV (95.5%) and T 1/2= 2.7 days) is a well-known therapeutic beta emitter in the field of nuclear medicine, and is being used for the treatment of many different cancers. In the present study, the Bremsstrahlung exposure induced by Au in different human tissues, DNA and RNA has been calculated. The specific Bremsstrahlung constant (P Br), Probability of energy loss by beta during Bremsstrahlung emission (P Br) and Bremsstrahlung activity (A release) Brwere estimated. We strongly recommend these parameters should be considered in absorbed dose calculations of radionuclide therapy via 198Au.