Published in
American Society of Hematology, Blood, 26(127), p. 3431-3438
DOI: 10.1182/blood-2016-03-700336
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- American Society of Hematology
- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [openaccess.sgul.ac.uk] | PDF
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Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives
Journal article published in 2016 by
Julio Lahoz-Beneytez,
Marjet Elemans 
,
Yan Zhang,
Raya Ahmed,
Arafa Salam,
Michael Block,
Christoph Niederalt,
Becca Asquith ,
Derek Macallan
,
Yan Zhang,
Raya Ahmed,
Arafa Salam,
Michael Block,
Christoph Niederalt,
Becca Asquith ,
Derek Macallan
This paper is available in a repository.
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Abstract
Key Points Mechanistic modeling of stable isotope labeling verifies human neutrophil half-lives of 13-19 h in contrast to recent estimates of >3 days. Human neutrophil kinetics can be measured using a single-dose deuterium-labeled glucose protocol.