Dissemin is shutting down on January 1st, 2025

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Elsevier, Biochemical and Biophysical Research Communications, 1(456), p. 398-402, 2015

DOI: 10.1016/j.bbrc.2014.11.095

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Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells

Journal article published in 2015 by Lesley A. Wilson, Lynn McKeown ORCID, Sarka Tumova, Jing Li, David J. Beech
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

•Knockdown of CRACR2A lacks effect on CRAC channels in endothelial cells.•Knockdown of CRACR2A depletes a protein twice the mass of CRACR2A.•A long variant of CRACR2A, CRACR2A-L, occurs in endothelial cells.•CRACR2A-L is a previously unrecognised EF-hand-containing Rab GTPase.•CRACR2A-L has a positive role in endothelial tube formation.