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Elsevier, Psychiatry Research, 1(199), p. 74-76, 2012

DOI: 10.1016/j.psychres.2012.03.048

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Pharmacogenetics of glutamate system genes and SSRI-associated sexual dysfunction

This paper is available in a repository.
This paper is available in a repository.

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Abstract

We examined whether polymorphisms in the GRIK2, GRIA3, and GRIA1 genes were associated with SSRI-associated sexual well-dysfunction in 114 participants treated for depression. One polymorphism in GRIA1 (rs1994862) was associated with arousal dysfunction, providing further evidence for the role of GRIA1 in mechanisms underlying SSRI-associated sexual side effects.