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Lippincott, Williams & Wilkins, Medicine, 1(95), p. e2050, 2016

DOI: 10.1097/md.0000000000002050

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Recurrent Hemolytic and Uremic Syndrome Induced by Escherichia Coli:

Journal article published in 2016 by Morgane Commereuc, François-Xavier Weill ORCID, Estelle Loukiadis, Christophe Ridel, Eric Rondeau, Malika Gouali, Audrey Gleizal, Veronique Fremeaux-Bacchi, Raphaël Kormann ORCID, Alexandre Hertig
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A widespread belief is that typical hemolytic and uremic syndrome (HUS) does not recur. We report the case of a patient infected twice with raw milk taken from his own cow and containing a Shiga toxin-producing Escherichia coli O174:H21 that induced recurrent HUS causing severe renal and cerebral disorders. A genomic comparison of the human and bovine Shiga toxin-producing Escherichia coli O174:H21 isolates revealed that they were identical.Typical HUS may recur. Since milk from this animal was occasionally distributed locally, thereby posing a serious threat for the whole village, this particular cow was destroyed.