Dissemin is shutting down on January 1st, 2025

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Journal of Rheumatic Diseases, 3(22), p. 200

DOI: 10.4078/jrd.2015.22.3.200

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Hepatic Sarcoidosis in a Patient with Chronic Hepatitis B Virus Infection

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Sarcoidosis is a systemic inflammatory granulomatous disease affecting multiple organs, including liver, spleen, heart, eyes, and skin. Liver involvement is reported in 11.5% of cases and many studies have reported on the association between hepatitis C virus infection and sarcoidosis. However, the role of hepatitis B virus (HBV) infection as a trigger for sarcoidosis has never been reported. We describe a case of hepatic sarcoidosis in a patient with chronic hepatitis B infection, with a possible link between the two. It is the first case report of a patient with interferon-α-naïve chronic HBV infection presenting with hepatic sarcoidosis accompanied by portal hypertension and liver cirrhosis.