Today we have to face new challenges about decreasing water resources, wastewater treatment, limited spaces and ecological preservation. This problem must be solved in a sustainable way using innovative water management strategies that combine technology with landscape design by enhancing ecosystem services provision. An effective way of tackling this problem is to use Constructed Treatment Wetlands (CTW) as low-cost alternative to conventional secondary or tertiary wastewater treatment. The aim of this paper is to evaluate their multifunctional role in terms of biodiversity and ecosystem services’ enhancement by taking into account a case study in southern Italy. For this purpose an annual monitoring of fauna and vegetation has been carried out in order to identify species of national and international interest strongly related to the new habitats availability. Results have shown the ability of CTW in providing ancillary benefits, well beyond the primary aim of water purification, such as sustaining wildlife habitats and biodiversity at local and global scales, as well as its potential role in terms of recreational and educational opportunities.