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Wiley, Fundamental & Clinical Pharmacology, 1(29), p. 10-20, 2014
DOI: 10.1111/fcp.12091
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Pharmacology and mechanisms of action of new oral anticoagulants
Journal article published in 2014 by
Joe‐Elie Salem,
Pierre Sabouret,
Christian Funck‐Brentano,
Jean‐Sebastien Hulot 
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Abstract
The new oral anticoagulants are announced as an important therapeutic revolution, particularly after their approval by authorities for stroke prevention in atrial fibrillation. However, the pharmacology of these new drugs is not homogeneous. In this review, we summarize the main pharmacological characteristics of the new direct anti-Xa and anti-IIa agents.This article is protected by copyright. All rights reserved.