In a first experiment, 11 neglect patients repeatedly bisected the elongated caricature of a basset hound with head on the right and tail on the left side with respect to the viewer. On the last (critical) trial, in which the figure was left-right reversed, the bisection error towards the ipsilesional side reversed its direction in three patients and significantly decreased in one patient. In a second experiment, 13 different neglect patients had to bisect the elongated caricature of the basset hound with head on the left and tail on the right side. On the last trial, the bisection error reversed its direction in three patients and significantly decreased in three patients. These results suggest that object-centred neglect (OCN) may affect newly established knowledge about the canonical orientation of a non-verbal visual stimulus.