This article prognosticates the hydrocarbon generation potential of core samples from fields A, B, C and D in Niger delta, Nigeria. The objectives of this study are to characterize the quality of these core samples by organic geochemical analyses. A total of ten core samples collected from fields A, B, C and D in Niger delta were analyzed using total organic carbon (TOC) content analysis, rock-eval pyrolysis technique. The analytical results of the studied core samples reveal that they have generally high total organic carbon contents (TOC), suggesting that conditions in the Niger delta favour organic matter production and preservation. There is a variation in the kerogen types and this may be attributed to the relative stratigraphic positions of the core samples within the Niger delta. The rock-eval results indicate that the samples from fields C and D contain predominantly Type II kerogen with a capacity to generate oil and gas and hence have good generative potential. The samples from fields A and B contain mainly Type III kerogen and are gas-prone with moderate generative potential.