Purpose: The purpose of the study was to evaluate if the Weight Control Perceived Self-efficacy Inventory (WC-PSE) is reproducible in a Mexican college population. Methods and materials: This is an observational and prolective process study. Sixty subjects from two geographical regions of Mexico were invited to answer the WC-PSE on two separate occasions. Findings: The Content Validity Index was 0.96. The mean difference in the test retest was <4 in all domains; the intra-class correlation coefficient was >0.7; Cronbach’s coefficient was α=.95. The inventory was sensitive to detecting differences according to gender and degrees of body mass index. Conclusion: The WC-PSE inventory is reproducible and sensitive for application to a Mexican college population.