Oxford University Press (OUP), Bioinformatics, 11(30), p. 1539-1546
DOI: 10.1093/bioinformatics/btu072
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Motivation: DNA copy number profiles characterize regions of chromosome gains, losses and breakpoints in tumor genomes. Although many models have been proposed to detect these alterations, it is not clear which model is appropriate before visual inspection the signal, noise and models for a particular profile.