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Hindawi, Journal of Chemistry, (2013), p. 1-7, 2013

DOI: 10.1155/2013/636280

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Alkylation and 1,3-Dipolar Cycloaddition of 6-Styryl-4,5-dihydro-2H-pyridazin-3-one: Synthesis of NovelN-Substituted Pyridazinones and Triazolo[4,3-b]pyridazinones

Journal article published in 2013 by Souad Mojahidi, Hanan Sekkak, El Mostapha Rakib, Maria G. P. M. S. Neves, Maria A. F. Faustino, José A. S. Cavaleiro ORCID, Hafid Zouihri
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Some newN-substituted pyridazinones and triazolo[4,3-b]pyridazinones were synthesized, respectively, by simple alkylation and 1,3-dipolar cycloaddition of pyridazin-3-one with nitrile imines. The regioselectivity of the reactions was ascertained by1H,13C NMR spectroscopy and X-ray diffraction of the synthesized compounds.