Published in
Society of Hospital Pharmacists of Australia, Journal of Pharmacy Practice and Research, 1(38), p. 55-57, 2008
DOI: 10.1002/j.2055-2335.2008.tb00798.x
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Cytochrome P450 Part 1: Multiplicity and Function
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Abstract
While new cytochrome P450 (CYP450) enzymes continue to be identified, it is now possible to predict with some confidence the total number of human CYP450 enzymes. This review is an update of the CYP450 superfamily of drug metabolising enzymes. It comprises a brief history of CYP450 research, outlines the standard P450 nomenclature system, and describes CYP450 multiplicity, structure and function. J Pharm Pract Res 2008; 38: 55-7.