Published in
Cell Press, Current Biology, 17(16), p. R673-R675, 2006
DOI: 10.1016/j.cub.2006.08.014
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Cell Signalling: Changing Shape Changes the Signal
Journal article published in 2006 by
Martin Howard 
This paper is made freely available by the publisher.
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Abstract
Recent experiments have revealed the existence of subcellular gradients of signalling molecules. A new modelling study shows that changes in cell shape or size allow gradient-controlled pathways to be turned on or off simply by altering the distance between the signal source and targets.