Carbon Nanodots Featuring Efficient FRET for Real-Time Monitoring of Drug Delivery and Two-Photon Imaging
Journal article published in 2013 by
Jing Tang 
,
Biao Kong,
Hao Wu,
Ming Xu,
Yongcheng Wang ,
Yanli Wang,
Dongyuan Zhao,
Gengfeng Zheng
,
Biao Kong,
Hao Wu,
Ming Xu,
Yongcheng Wang ,
Yanli Wang,
Dongyuan Zhao,
Gengfeng Zheng
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Abstract
A FRET-based carbon nanodot (CDot) drug delivery platform has been developed. These CDots offer excellent biocompatibility, stable fluorescence, and efficient FRET between CDots and the attached fluorescent drug molecules, such as doxorubicin, enabling enhanced drug delivery, convenient cell imaging, and real-time monitoring of drug release. Moreover, the FRET-based two-photon imaging and drug tracking in deep tissues are also demonstrated.