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Springer, Photochemical & Photobiological Sciences, 10(11), p. 1520-1523, 2012

DOI: 10.1039/c2pp25156f

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Susceptibility of non-enveloped DNA- and RNA-type viruses to photodynamic inactivation

Journal article published in 2012 by Liliana Costa, João P. C. Tomé ORCID, Maria G. P. M. S. Neves, Augusto C. Tomé, José A. S. Cavaleiro ORCID, Angela Cunha, Maria A. F. Faustino, Adelaide Almeida
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The comparative susceptibility of DNA- and RNA-type viruses to photodynamic inactivation has not yet been clearly addressed. In this study the effect of the tricationic porphyrin Tri-Py(+)-Me-PF on the inactivation of four DNA and three RNA non-enveloped phages was compared. The results obtained show that the photodynamic efficiency varied with the phage type, the RNA-type phages being much more easily photoinactivated than the DNA-type ones.