Elsevier, Physica A: Statistical Mechanics and its Applications, 21-22(390), p. 4038-4044
DOI: 10.1016/j.physa.2011.05.032
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In this work we study, at the single molecular level, the thermodynamic and dynamic characteristics of an enzymatic reaction comprising a rate limiting step. We investigate how the stability of the enzyme-state stationary probability distribution, the reaction velocity, and its efficiency of energy conversion depend on the system parameters. We employ in this study a recently introduced formalism for performing a multiscale thermodynamic analysis in continuous-time discrete-state stochastic systems. ; Comment: In Press in Physica A