Aquatic biotopes are, due to their unique features, among the most disposed ecosystems to bioinvasions. Serbian waters are not an exception, with a increasing colonization by allochthonous organisms observed there during the last few decades. Non-indigenous aquatic species were found among plants, vertebrates and invertebrates. One of the most invasive aquatic macroinvertebrate species found in the region is the Chinese pond mussel Anodonta (Sinanodonta) woodiana (Rea, 1834). The species is dispersed along lowland rivers, associated wetlands and manmade canals. Heavily modified and artificial aquatic habitats, with high silting rates, were found to be especially suitable for population by A. woodiana. A mass occurrence of Chinese mussel was observed among these habitats, particularly where bottom substrata were characterised by the domination of silt-clay.