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2011 Conference Record of the Forty Fifth Asilomar Conference on Signals, Systems and Computers (ASILOMAR)

DOI: 10.1109/acssc.2011.6190037

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Modeling latency and shape changes in trial based neuroimaging data

Proceedings article published in 2011 by Morten Morup ORCID, Lars Kai Hansen, Kristoffer Hougaard Madsen
This paper is available in a repository.
This paper is available in a repository.

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Abstract

To overcome poor signal-to-noise ratios in neuroimaging, data sets are often acquired over repeated trials that form a three-way array of space×time×trials. As neuroimaging data contain multiple inter-mixed signal components blind signal separation and decomposition methods are frequently invoked for exploratory analysis and as a preprocessing step for signal detection. Most previous component analyses have avoided working directly with the tri-linear structure, but resorted to bi-linear models such as ICA, PCA, and NMF. Multi-linear decomposition can exploit consistency over trials and contrary to bi-linear decomposition render unique representations without additional constraints. However, they can degenerate if data does not comply with the given multi-linear structure, e.g., due to time-delays. Here we extend multi-linear decomposition to account for general temporal modeling within a convolutional representation. We demonstrate how this alleviates degeneracy and helps to extract physiologically plausible components. The resulting convolutive multi-linear decomposition can model realistic trial variability as demonstrated in EEG and fMRI data.