Published in
Elsevier, Psychiatry Research, 3(210), p. 1290-1292
DOI: 10.1016/j.psychres.2013.09.016
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Neurotransmitter receptor and regulatory gene expression in peripheral blood of Brazilian drug-naive first-episode psychosis patients before and after antipsychotic treatment
Journal article published in 2013 by
Vanessa Kiyomi Ota 
,
Cristiano Noto ,
Ary Gadelha,
Marcos Leite Santoro,
Patricia Natalia Silva,
Maria Isabel Melaragno,
Marília de Arruda Cardoso Smith,
Quirino Cordeiro,
Rodrigo Affonseca Bressan,
Sintia Iole Belangero
,
Cristiano Noto ,
Ary Gadelha,
Marcos Leite Santoro,
Patricia Natalia Silva,
Maria Isabel Melaragno,
Marília de Arruda Cardoso Smith,
Quirino Cordeiro,
Rodrigo Affonseca Bressan,
Sintia Iole Belangero
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Abstract
Little is known about how genes expressed in blood relate to schizophrenia or antipsychotic use. We analyzed gene expression in 10 first-episode psychosis patients and nine controls using PCR Arrays. GABRR2 and CHRNA3 were found to be differentially expressed after risperidone treatment. These genes may be regulated by antipsychotic use.