In this study, the possible genotoxic potential of ben-furacarb, one of the widely used carbamate insecticides in agriculture, was evaluated by performing the micronucleus assay in human peripheral blood lymphocyte cultures. It was determined that CBPI (%) (cytokinesis-block proliferation index) was reduced at all concentrations of benfuracarb in both 24-and 48-h treatment periods. CBPI rate (%) was revealed to be statistically significant for both control and negative control groups at 500, 750, and 1000 µg/ml concentrations of 24-h treatment period as well as 750 and 1000 µg/ml concentrations of 48-h treatment period. This reduction in the CBPI (%) indicates that benfuracarb can be regarded to be cytotoxic on human cells in vitro, and requires further in vivo studies to clarify the actual geno-toxicity of this compound.