American Society of Hematology, Blood, 15(125), p. 2370-2380, 2015
DOI: 10.1182/blood-2014-09-602565
Full text: Download
Key Points Benign (ie, IgM MGUS and smoldering WM) clonal B cells already harbor the phenotypic and molecular signatures of the malignant WM clone. Multistep transformation from benign (ie, IgM MGUS and smoldering WM) to malignant WM may require specific copy number abnormalities.