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Taylor and Francis Group, Synthetic Communications, 4(23), p. 473-486

DOI: 10.1080/00397919308009802

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Extension of the Bobbitt Acetal Cyclization to the Elaboration of 1-Hydroxymethyl-Substituted Simple Tetrahydroisoquinolines. A New Synthesis of Calycotomine

Journal article published in 1993 by Teodoro S. Kaufman ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Aromatic benzyloxymethyl ketones are convenient intermediates for the elaboration, via the Bobbitt acetal cyclization, of 1-hydroxymethyl-substituted simple tetrahydroisoquinolines, such as calycotomine and one bearing the 1,7,8-oxygenated substitution pattern of MY336-a.