Published in
Chemical Society of Japan, Chemistry Letters, 1(39), p. 72-73, 2010
DOI: 10.1246/cl.2010.72
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DNA Compaction on Histone Mimics Prepared from Silica Nanoparticles
Journal article published in 2010 by
Toshio Takenaka,
Anatoly A. Zinchenko,
Kenichi Yoshikawa 
,
Shizuaki Murata
,
Shizuaki Murata
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Abstract
Silica nanoparticles, the surface of which was modified by a 3-aminopropylsilyl group, compacted gene-size DNA in aqueous solutions in the presence of Na(+) or K(+). The DNA-compaction efficiency of histone-size (10 nm diameter) nanoparticles is greater than that of large (100 nm) nanoparticles under similar experimental conditions.