Springer Verlag, Lecture Notes in Computer Science, p. 36-45
DOI: 10.1007/978-3-642-15835-3_4
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The Cardiac Atlas Project (CAP) is a NIH sponsored international col-laboration to establish a web-accessible structural and functional atlas of the nor-mal and pathological heart as a resource for the clinical, research and educational communities. An initial goal of the atlas is to facilitate statistical analysis of regional heart shape and wall motion characteristics, and characterization of re-modeling, between and within population groups. The two main early contributing studies are the Multi Ethnic Study of Atherosclerosis (MESA) and the Defibrilla-tors to Reduce Risk by Magnetic Resonance Imaging Evaluation (DETERMINE) clinical trial. De-identified image and text data from 2864 asymptomatic volunteers from MESA, and 470 myocardial infarction cases from DETERMINE, are cur-rently available in the CAP database. DICOM images were de-identified using HIPAA compliant software based on tools provided by the Center for Computa-tional Biology at UCLA. Only those cases with informed consent and IRB ap-proval compatible with the CAP were included. Researchers requesting permission to access CAP data can apply through the CAP website (www.cardiacatlas.org). All proposals for data access must be approved by the data contributors, and appli-cants must sign a data transfer agreement with each study from which data is re-quested. Software to visualize cardiac images and create 3D mathematical models, developed in the CAP, is available open-source from the website.