Published in
Wiley, Journal of Medical Virology, 2(63), p. 189-195, 2001
DOI: 10.1002/1096-9071(20000201)63:2<189::aid-jmv1014>3.0.co;2-h
Wiley, Journal of Medical Virology, 2(63), p. 189-195
DOI: 10.1002/1096-9071(20000201)63:2<189::aid-jmv1014>3.3.co;2-8
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TT virus levels in the plasma of infected individuals with different hepatic and extrahepatic pathology
,
Maria Linda Vatteroni,
Giulia Freer,
Claudia Fornai,
Francesca Casula,
Santino Marchi,
Pietro Ciccorossi,
Paolo Rovero ,
Mauro Bendinelli
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Abstract
TT virus (TTV) infection is extremely widespread in the general population. A sensitive real-time PCR assay was developed that quantitated accurately the most prevalent TTV genotypes in Italy. When used to test 217 individuals for TTV viraemia, the overall prevalence was 94%. Viraemia levels varied widely amongst individual subjects, with no major differences related to gender or age. The highest TTV titres were in haemophiliacs and in patients with non-A–E hepatitis, but they did not differ from the group with miscellaneous diseases. HIV- and HCV-infected subjects and patients with primary liver diseases had TTV loads similar to those of healthy individuals. J. Med. Virol. 63:189–195, 2001. © 2001 Wiley-Liss, Inc.