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Portland Press, Biochemical Journal, 2(310), p. 383-387, 1995

DOI: 10.1042/bj3100383

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Evolutionary conservation of the vertebrate Ah (dioxin) receptor: Amplification and sequencing of the PAS domain of a teleost Ah receptor cDNA

Journal article published in 1995 by M. E. Hahn ORCID, S. I. Karchner
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The PAS domain of a teleost Ah receptor was amplified using reverse transcription-PCR with degenerate primers containing inosine. The deduced amino acid sequence of the amplified cDNA fragment was 62-64% identical with the PAS domains of mammalian Ah receptors. These data demonstrate the homology of Ah receptors in mammals and fish, and reveal regions of this protein that are highly conserved between these diverse vertebrate groups.