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Royal Society of Chemistry, RSC Advances, 92(4), p. 51032-51037

DOI: 10.1039/c4ra07754g

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Designing BODIPY-based probes for fluorescence imaging of β-amyloid plaques

Journal article published in 2014 by Fazli Sozmen, Safacan Kolemen, Henri-Obadja Kumada, Masahiro Ono, Hideo Saji, Engin U. Akkaya ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Styryl-congutated BODIPY dyes which are structurally similar to known Aβ peptide binding dyes, were designed and synthesized. The binding is accompanied by a large increase in the emission intensity in all cases, suggesting a high potential for use in the fluorescence imaging of Aβ plaques.