BILATERAL TOTAL HIP AND KNEE ARTHROPLASTY IN A PATIENT WITH RHEUMATOID ARTHRITIS. A CASE REPORT Saša Stojanović1, Predrag Stojiljković1, Golubović Ivan1, Ivica Lalić4, Danilo Stojiljković2, Marko Kadija5, Ivana Golubović1, Zoran Radovanović2, Mila Janjić2, Zoran Golubović1, Miroslav Trajanović3 Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder of unknown etiology characterized by synovial hyperplasia and resulting joint destruction. Despite reduced needs for total joint arthroplasty in the treatment of end-stage damage of the hip and knee in RA, many patients still require hip and knee arthroplasty to restore the hip function and quality of life. We present the surgical treatment of young RA patient with bilateral total hip and bilateral knee arthroplasty at the Clinic of Orthopaedics and Traumatology Clinical Center Niš. Male patient with seropositive RA was implanted with bilateral total hip and knee over a period of 4 years (2008 to 2011). At the time of the first left hip arthroplasty, the patient was 32 years old. Surgical treatment in all arthroplasty procedures passed without complications. At the control examination 3 years after the last surgery, the patient was walking without mobility aids. His walk was safe and stable. The post-operative scars on hips and knees were stable, with no signs of inflammation. The flexion of the knees was possible till 110 degrees, and the extension to the full capacity.The patient resumed his work and life activities, and now he works as a game warden. He normally performs everyday activities, including climbing to the watchtower. Total hip and knee arthroplasty in rheumathoid arthritis patients with advanced joint destruction is a successful solution. Acta Medica Medianae 2014;53(4):30-36. Key words: rheumatoid arthritis, bilateral arthroplasty, hip, knee Clinic of Orthopaedic and Traumatology, Clinical Center Niš, Serbia1 University of Niš, Faculty of Medicine in Niš, Serbia2 University of Niš, Faculty of Mechanical Engineering in Niš, Serbia3 Medical Faculty in Novi Sad, Serbia4 School of Medicine in Belgrade, Serbia5 Contact: Saša Stojanović Bul.dr. Zorana Đinđića 48, 18000 Niš, Serbia E-mail: sasastojanovic66@hotmail.com