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Oxford University Press, Journal of Molecular Cell Biology, 6(5), p. 432-434

DOI: 10.1093/jmcb/mjt036

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MiR-133 links to energy balance through targeting Prdm16

Journal article published in 2013 by Weiyi Liu, Shihuan Kuang ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Prdm16 is a master regulator of brown adipogenesis and thus plays critical roles in body energy expenditure. Three recent studies identify microRNA-133 (miR-133) as a novel regulator of Prdm16 in muscle stem cells and both brown and white adipocytes, and point miR-133 as a potential therapeutic target to treat obesity and Type 2 diabetes.