Published in
American Society of Hematology, Blood, 2(126), p. 212-221, 2015
DOI: 10.1182/blood-2015-02-626754
Links
- ORCID
- American Society of Hematology | PDF
- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
Tools
Mechanisms of PD-L1/PD-1–mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model
Journal article published in 2015 by
Fabienne McClanahan 
,
John C. Riches,
Shaun Miller,
William P. Day,
Eleni Kotsiou,
Donna Neuberg ,
Carlo M. Croce ,
Melania Capasso ,
John G. Gribben
,
John C. Riches,
Shaun Miller,
William P. Day,
Eleni Kotsiou,
Donna Neuberg ,
Carlo M. Croce ,
Melania Capasso ,
John G. Gribben
Distributing this paper is prohibited by the publisher
Full text: Unavailable
Preprint: archiving forbidden
Published version:
archiving forbidden
Data provided by 
Abstract
Key Points PD-L1/PD-1–mediated CD8 T-cell dysfunction develops with CLL in different organs, and similarities to aging-related immune defects exist. PD-1+ normal T cells have markedly different effector functions than PD-1+ CLL T cells.