American Society of Hematology, Blood, 2(126), p. 212-221, 2015
DOI: 10.1182/blood-2015-02-626754
Full text: Unavailable
Key Points PD-L1/PD-1–mediated CD8 T-cell dysfunction develops with CLL in different organs, and similarities to aging-related immune defects exist. PD-1+ normal T cells have markedly different effector functions than PD-1+ CLL T cells.