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Nature Research, Scientific Reports, 1(5), 2015

DOI: 10.1038/srep14622

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Quantifying barcodes of dendritic spines using entropy-based metrics

Journal article published in 2015 by D. Viggiano, Srivastava Dp, D. P. Srivastava, L. Speranza, C. Perrone Capano, G. C. Bellenchi, Bellenchi Gc, U. di Porzio, N. J. Buckley ORCID, Buckley Nj
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

AbstractSpine motility analysis has become the mainstay for investigating synaptic plasticity but is limited in its versatility requiring complex, non automatized instrumentations. We describe an entropy-based method for determining the spatial distribution of dendritic spines that allows successful estimation of spine motility from still images. This method has the potential to extend the applicability of spine motility analysis to ex vivo preparations.