Dissemin is shutting down on January 1st, 2025

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Nature Research, Scientific Reports, 1(5), 2015

DOI: 10.1038/srep14622

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Quantifying barcodes of dendritic spines using entropy-based metrics

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

AbstractSpine motility analysis has become the mainstay for investigating synaptic plasticity but is limited in its versatility requiring complex, non automatized instrumentations. We describe an entropy-based method for determining the spatial distribution of dendritic spines that allows successful estimation of spine motility from still images. This method has the potential to extend the applicability of spine motility analysis to ex vivo preparations.