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Bentham Science Publishers, Letters in Drug Design & Discovery, 7(2), p. 507-515

DOI: 10.2174/157018005774479104

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Design of Selective Inhibitors of Tyrosine Kinase 2

Journal article published in 2005 by Kristin Tondel, Finn Drablos ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Selective inhibitors of tyrosine kinase 2 (Tyk2) were searched for using database screening, de novo ligand design and computational docking in Tyk2 and seven other protein kinases. None of the structures in the National Cancer Institute database seem to inhibit Tyk2 selectively, but five of the designed structures seem promising.