The asymmetric unit of the title compound, C21H23N5OS2, contains two independent chiral mol­ecules. The two phenyl rings of one mol­ecule form a dihedral angle of 51.95 (7)° and the distance between their centroids is 4.345 (1) Å. In the other mol­ecule, the phenyl rings form a dihedral angle of 58.79 (8)° with a ring centroid–centroid distance of 4.435 (2) Å. An intra­molecular O—H⋯N hydrogen bond occurs in each independent mol­ecule. The crystal packing is stabilized by and inter­molecular N—H⋯O and N—H⋯S hydrogen bonds and C—H⋯S inter­actions.