In this paper an incremental analog-to-digital converter (ADC), designed as part of the signal-conditioning circuitry for a tissue impedance measurement system, is presented. Continuous-time design techniques have been used for the development of a modified implementation of the conversion algorithm, with respect to its discrete-time counterpart. In order to reduce the influence of the nonidealities, analog and digital corrections have been also implemented. A first prototype in 0.8 μm CMOS technology has been fabricated and tested. Simulation and experimental results are reported.