Sedimentary deposits from two Middle to Late Pleistocene glaciations and intervening non-glacial in- tervals exposed along the White River in southwest Yukon, Canada, provide a record of environmental change for much of the past 200 000 years. The study sites are beyond the Marine Isotope stage (MIS) 2 glacial limit, near the maximum regional extent of Pleistocene glaciation. Non-glacial deposits include up to 25 m of loess, peat and gravel with paleosols, pollen, plant and insect macrofossils, large mammal fossils and tephra beds. Finite and non-finite radiocarbon dates, and twelve different tephra beds constrain the chronology of these deposits. Tills correlated to MIS 4 and 6 represent the penultimate and maximum Pleistocene glacial limits, respectively. The proximity of these glacial limits to each other, compared to limits in central Yukon, suggests precipitation conditions were more consistent in south- west Yukon than in central Yukon during the Pleistocene. Conditions in MIS 5e and 5a are recorded by two boreal forest beds, separated by a shrub birch tundra, that indicate environments as warm or warmer than present. A dry, treeless steppe-tundra, dominated by Artemisia frigida, upland grasses and forbs existed during the transition from late MIS 3 to early MIS 2. These glacial and non-glacial deposits constrain the glacial limits and paleoenvironments during the Middle to Late Pleistocene in southwest Yukon.